Congenital heart disease (CHD), a life-threatening birth disorder, is the most common genetic disorder with an incidence rate as high as 1% in neonates (36,000 cases in 2006). Amongst these children, one out of four has single ventricle anomaly. As a palliative rather than a curative means for vascular reconstruction, the “Fontan” palliation has been used to produce stable hemodynamic states, at least for a limited period of time. However, the majority of post-Fontan patients faces a high risk of mortality and morbidity , and will have to undergo heart transplant eventually due to the excess load imposed on the single ventricle by the systemic resistance.
Patient-Specific Fluid Structure Interaction Simulation Applied to Evaluating Hemodynamics Within the Total Cavopulmonary Connection
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Wang, R, Lacour-Gayet, FG, Lanning, C, Hunter, K, & Shandas, R. "Patient-Specific Fluid Structure Interaction Simulation Applied to Evaluating Hemodynamics Within the Total Cavopulmonary Connection." Proceedings of the ASME 2007 Summer Bioengineering Conference. ASME 2007 Summer Bioengineering Conference. Keystone, Colorado, USA. June 20–24, 2007. pp. 517-518. ASME. https://doi.org/10.1115/SBC2007-176494
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