Intracranial aneurysm rupture is the leading cause of subarachnoid hemorrhage in the United States and is associated with higher fatality rates than ischemic stroke. There is currently no objective diagnostic means to identify aneurysms that are at high risk for rupture despite significant improvements in treatment. Often with no warning signs prior to aneurysm rupture such as the transient ischemic attack in ischemic stroke, the need to develop a method for detecting aneurysm instability is necessary.

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