The New Zealand White (NZW) rabbit is often used as an animal model in posterolateral intrertransverse lumbar fusions . Qualitative measures, such as manual palpation and radiographs, have been used to assess fusion mass . However, an evaluation by sacrifice and biomechanical testing is the gold standard for quantitative data. A non-invasive approach to quantitatively assess the mechanics of spinal fusion could allow longitudinal studies with decreased need for animal sacrifice.
- Bioengineering Division
Mechanical Validation of Computed Tomographic Quantification of Posterolateral Intertransverse Lumbar Fusion
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O’Brien, M, Dai, Y, & Niebur, GL. "Mechanical Validation of Computed Tomographic Quantification of Posterolateral Intertransverse Lumbar Fusion." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 237-238. ASME. https://doi.org/10.1115/SBC2008-192279
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