Endovascular therapies are an evolving form of treatment for stenosed atherosclerotic blood vessels. In particular, stenting and angioplasty of the carotid artery has recently gained more attention. Due to risk of periprocedural distal embolization, cerebral protection devices such as embolic protection filters (EPFs), which maintain distal perfusion during the intervention, have been developed to capture embolized plaque particles. This investigation studied in vitro the effects of a deployed EPF on flow rate in the internal carotid artery. The pseudopermeability of each device was calculated by maintaining a constant pressure gradient during its deployed state and after injection of emboli by adjusting the flow rate. High resolution images were used to calculate the porosity of each device. Experimentally-determined permeability and porosity can be used in computational fluid dynamics simulations as a design optimization approach to determine the optimal pore size for each EPF.
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ASME 2008 Summer Bioengineering Conference
June 25–29, 2008
Marco Island, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4321-5
PROCEEDINGS PAPER
Permeability and Porosity of Embolic Protection Filters: An Experimental Study
Gail M. Siewiorek,
Gail M. Siewiorek
Carnegie Mellon University, Pittsburgh, PA
Search for other works by this author on:
Ender A. Finol
Ender A. Finol
Carnegie Mellon University, Pittsburgh, PA
Search for other works by this author on:
Gail M. Siewiorek
Carnegie Mellon University, Pittsburgh, PA
Ender A. Finol
Carnegie Mellon University, Pittsburgh, PA
Paper No:
SBC2008-192483, pp. 753-754; 2 pages
Published Online:
March 13, 2014
Citation
Siewiorek, GM, & Finol, EA. "Permeability and Porosity of Embolic Protection Filters: An Experimental Study." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 753-754. ASME. https://doi.org/10.1115/SBC2008-192483
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