Design Optimization of a Wearable Artificial Pump-Lung Device With Computational Modeling

The heart-lung machine has been commonly used to replace or supplement the functions of both the heart and lung in the open heart surgery and extracorporeal membrane oxygenation (ECMO). Although ECMO devices are efficient on respiratory support, this traditional system consists of multiple components and is bulky. Furthermore, ECMO devices are associated with clinical complications as well as the necessity of being confined to the bed. To eliminate these, we aimed to design and develop a wearable artificial pump lung (APL) device.