Vulnerable plaques are characterized by the presence of a large lipid pool, which is separated from the lumen by a thin fibrous cap. Rupture of this fibrous cap is generally regarded as one of the main underlying causes of cardiovascular events (1). The composition of the plaque plays a crucial role in the rupture process: it determines how blood pressure is translated into stresses in the wall, and composition also determines the strength of the tissue.
- Bioengineering Division
Location of Plaque Ulceration in Human Coronary Arteries is Related to Shear Stress
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van der Giessen, A, Wentzel, J, Groen, H, de Feyter, P, van de Vosse, F, van der Steen, A, & Gijsen, F. "Location of Plaque Ulceration in Human Coronary Arteries is Related to Shear Stress." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 31-32. ASME. https://doi.org/10.1115/SBC2010-19297
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