A rising therapy for liver tumor treatment is the local delivery of Yttrium-90 (90Y) radiation via the injection of radioactive microspheres into the hepatic arteries. The elevated arterial blood flow supplying the liver tumor(s) hopefully directs the microspheres towards tumor cells rather than healthy liver tissue. While limited in precise control of the microspheres, the therapy has been shown to have positive response rates on tumors that are nonresponsive to chemotherapy or are disqualified for surgical resection or ablation. Thus, research studies seeking to improve clinical 90Y-microsphere therapy are crucial to advancing radiation oncologists’ ability to effectively treat the increasing number of patients afflicted with liver tumors1,2.
- Bioengineering Division
Determination of Representative Pressure, Velocity and Flow Rate Waveforms in a Human Hepatic Artery System Afflicted With Metastatic Tumors
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Basciano, CA, Kleinstreuer, C, & Kennedy, AS. "Determination of Representative Pressure, Velocity and Flow Rate Waveforms in a Human Hepatic Artery System Afflicted With Metastatic Tumors." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1097-1098. ASME. https://doi.org/10.1115/SBC2011-53875
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