Atherosclerotic plaque progression involves biological, structural and mechanical factors. Previous work has shown that initiation and early progression of atherosclerotic plaque correlate negatively with flow wall shear stresses [1–2]. However, plaque growth functions based on patient-specific data to predict future plaque growth are lacking in the current literature. Six plaque growth functions based on fluid-structure-interaction (FSI) models and in vivo serial magnetic resonance image (MRI) data were proposed for progression prediction. This is to test the hypothesis that combining plaque morphology, plaque wall maximum principal stress (WS), strain (WSN) and flow maximum shear stress (FSS) could better predict plaque progression.
- Bioengineering Division
Plaque Growth Functions Combining Wall Stress, Flow Shear Stress and Morphology May Provide Better Prediction for Atherosclerosis Progression: 3D FSI Studies Based on In Vivo Serial MRI
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Yang, C, Canton, G, Yuan, C, Hatsukami, T, & Tang, D. "Plaque Growth Functions Combining Wall Stress, Flow Shear Stress and Morphology May Provide Better Prediction for Atherosclerosis Progression: 3D FSI Studies Based on In Vivo Serial MRI." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1119-1120. ASME. https://doi.org/10.1115/SBC2011-53100
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