Development of non-invasive diagnostic indices often requires accurate blood-flow calculation using physiologically realistic velocity profiles as boundary conditions. In this research, a methodology is being developed and validated that can directly use phase-contrast MR imaging (PC-MRI) based velocity measurement to perform blood-flow computation with patient-specific geometry. Using this methodology, the pressure drop can also be calculated non-invasively. Although the main focus of our research has been pulmonary insufficiency (PI) in tetralogy patients, our method can be employed in many other pathophysiologies. As a pilot study, the methodology is tested using a simple model of blood-flow through a straight artery of uniform cross-section.
- Bioengineering Division
Development of a Methodology for Direct Utilization of Phase-Contrast MRI in Hemodynamic Computations
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Das, A, Gottliebson, WM, Wansapura, J, & Banerjee, RK. "Development of a Methodology for Direct Utilization of Phase-Contrast MRI in Hemodynamic Computations." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1135-1136. ASME. https://doi.org/10.1115/SBC2011-53959
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