In the last years there is an increasing interest in patient-specific simulations of the fluid-structure interaction in aortic aneurysms, a.o. to better understand the growth and development of the aneurysm and to support diagnosis through assessment of its rupture potential. In order to verify these simulations, validation is an important and difficult task. Given ethical constraints, the slow time course of the disease in humans and the absence of true baseline data in a healthy aorta, these studies are difficult to perform in humans. This is particularly true for aneurysm rupture research, as rupture will normally be prevented by surgery and access to post-mortem tissue is not always possible. In order to overcome these problems an AAA mouse model can be used .
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Structural Simulation of a Mouse-Specific Abdominal Aorta
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Bols, J, Trachet, B, Degroote, J, De Santis, G, Mortier, P, Verhegghe, B, Segers, P, & Vierendeels, J. "Structural Simulation of a Mouse-Specific Abdominal Aorta." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 1147-1148. ASME. https://doi.org/10.1115/SBC2011-53635
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