The number of numerical studies predicting blood flow in intracranial aneurysms is rapidly increasing over the last years. Due to a high spatial as well as temporal resolution, computational fluid dynamics (CFD) approaches offer a high potential to investigate flow interaction within the human vascular system. However, state-of-the-art methods still underlie several assumptions, e.g., rigid vessel walls, analytical boundary conditions or the consideration of blood as a single-phase continuous fluid. In consequence, the acceptance of CFD is still limited among a majority of physicians . In order to overcome these reasonable doubts, simulations need to be validated via experiments. Therefore, two patient-specific intracranial aneurysms were measured by means of 7-Tesla magnetic resonance imaging (MRI). Afterwards, highly resolved numerical simulations were carried out and the peak-systolic velocity fields compared in a qualitative manner.
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Validation of Cerebral Blood Flow in Intracranial Aneurysms: CFD Versus 7 Tesla 4D PC-MRI
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Berg, P, Janiga, G, Stucht, D, Speck, O, & Thévenin, D. "Validation of Cerebral Blood Flow in Intracranial Aneurysms: CFD Versus 7 Tesla 4D PC-MRI." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT04A007. ASME. https://doi.org/10.1115/SBC2013-14289
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