Mitral valve (MV) disease is the most prevalent form of heart valve disease among the US population . MV disease can affect any one of the four components of the mitral valve: chordae tendinae, valve leaflets, papillary muscles or the supporting annulus. In one example of MV disease the annulus can become dilated, and this can subsequently lead to mitral valve insufficiency. Various surgical and catheter based techniques have been developed for repair or replacement of a dysfunctional MV, and many of these procedures involve suturing or anchoring devices directly to the annulus, thus restricting further dilatation of the annulus.
- Bioengineering Division
The Chink in the Armor of the Mitral Valve Annulus: The Irregular Distribution of Mechanical Properties
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Gunning, GM, Sheridan, WS, & Murphy, BP. "The Chink in the Armor of the Mitral Valve Annulus: The Irregular Distribution of Mechanical Properties." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT04A014. ASME. https://doi.org/10.1115/SBC2013-14465
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