The anterior cruciate ligament (ACL) is necessary for normal knee stability and movement. The ACL supports the knee and limits anterior translation of the femur beyond the tibia, which could cause a dislocation and fracture of bones in the knee. Unfortunately the ACL is also the most frequently injured ligament of the knee with severe disruptions requiring surgical intervention. One surgical option is replacement of the ligament with autografts, allografts, or artificial replacements. Unfortunately, all of these options have drawbacks.
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The Effect of Hydrogel Phase on Stress Relaxation Properties of a Novel Hydrogel Fibrous Composite Scaffold for Ligament Tissue Engineering
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Freeman, JW, Woods, MD, & Laurencin, CT. "The Effect of Hydrogel Phase on Stress Relaxation Properties of a Novel Hydrogel Fibrous Composite Scaffold for Ligament Tissue Engineering." Proceedings of the ASME 2008 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. Smart Materials, Adaptive Structures and Intelligent Systems, Volume 2. Ellicott City, Maryland, USA. October 28–30, 2008. pp. 687-689. ASME. https://doi.org/10.1115/SMASIS2008-631
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