The development of new coronary artery constitutive models is of critical importance in the design and analysis of coronary replacement grafts. In this study, a two-parameter logarithmic complementary energy function, with normalized measured force and internal pressure as the independent variables and strains as the dependent variables, was developed for healthy porcine coronary arteries. Data was collected according to an experimental design with measured force ranging from 9.8 to 201 mN and internal pressure ranging from 0.1 to 16.1 kPa (1 to 121 mmHg). Comparisons of the estimated constitutive parameters showed statistically significant differences between the left anterior descending [LAD] and right coronary artery [RCA], but no differences between the LAD and left circumflex [LCX] or between the LCX and RCA. Point-by-point strain comparisons confirm the findings of the model parameter study and isolate the difference to the axial strain response. Average axial strains for the LAD, LCX, and RCA are and respectively, at all physiologic loads, suggesting that the axial strains in the LAD are significantly higher than in the other regions.
Constitutive Modeling of Porcine Coronary Arteries Using Designed Experiments
Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING. Manuscript received January 2001; revised manuscript received November 2002. Associate Editor: J. D. Humphrey
- Views Icon Views
- Share Icon Share
- Search Site
Dixon, S. A., Heikes, R. G., and Vito, R. P. (April 9, 2003). "Constitutive Modeling of Porcine Coronary Arteries Using Designed Experiments ." ASME. J Biomech Eng. April 2003; 125(2): 274–279. https://doi.org/10.1115/1.1560138
Download citation file: