The objective of the present study was to perform biaxial testing and apply constitutive modeling to develop a strain energy function that accurately predicts the material behavior of the aortic valve leaflets. Ten leaflets from seven normal porcine aortic valves were biaxially stretched in a variety of protocols and the data combined to develop and fit a strain energy function to describe the material behavior. The results showed that the nonlinear anisotropic behavior of the aortic valve is well described by a strain energy function of two strain invariants, which uses only three coefficients to accurately predict the stress-strain behavior over a wide range of deformations. This structurally-motivated constitutive law has many applications, including computational modeling for clinical and engineering valve treatments.
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e-mail: kmn@kahuna.sdsu.edu
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August 2009
Research Papers
A Hyperelastic Constitutive Law for Aortic Valve Tissue
Karen May-Newman,
Karen May-Newman
Professor
Department of Mechanical Engineering,
e-mail: kmn@kahuna.sdsu.edu
San Diego State University
, San Diego, CA 92182-1323
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Charles Lam,
Charles Lam
Department of Mechanical Engineering,
San Diego State University
, San Diego, CA 92182-1323
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Frank C. P. Yin
Frank C. P. Yin
Department of Biomedical Engineering,
Washington University
, St. Louis, MO 63130
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Karen May-Newman
Professor
Department of Mechanical Engineering,
San Diego State University
, San Diego, CA 92182-1323e-mail: kmn@kahuna.sdsu.edu
Charles Lam
Department of Mechanical Engineering,
San Diego State University
, San Diego, CA 92182-1323
Frank C. P. Yin
Department of Biomedical Engineering,
Washington University
, St. Louis, MO 63130J Biomech Eng. Aug 2009, 131(8): 081009 (7 pages)
Published Online: July 6, 2009
Article history
Received:
October 27, 2008
Revised:
December 10, 2008
Published:
July 6, 2009
Citation
May-Newman, K., Lam, C., and Yin, F. C. P. (July 6, 2009). "A Hyperelastic Constitutive Law for Aortic Valve Tissue." ASME. J Biomech Eng. August 2009; 131(8): 081009. https://doi.org/10.1115/1.3127261
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