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Keywords: SPARC
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Journal Articles

Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse

Mitchel C. Whittal, Sara Molladavoodi, Derek P. Zwambag, Magali Millecamps, Laura S. Stone, Diane E. Gregory
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. February 2021, 143(2): 024501.
Paper No: BIO-20-1065
DOI: https://doi.org/10.1115/1.4047995
Published Online: October 8, 2020
...Mitchel C. Whittal; Sara Molladavoodi; Derek P. Zwambag; Magali Millecamps; Laura S. Stone; Diane E. Gregory Intervertebral disc (IVD) degeneration is associated with low back pain (LBP) and accompanied by mechanical changes to the spine. Secreted protein acidic and rich in cysteine (SPARC...
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Topics: Intervertebral discs, Lumbar spine, Stiffness, Mechanical testing, Proteins, Mechanical properties