... of a bone shaft segment, the Young's modulus values obtained (between 9518.29 MPa and 14181.15 MPa) are considered average values for the whole tissue, highlighting some intersubject variability. The material microstructure has also been studied through histological analysis, and bone-to-bone comparisons...

... it. We propose a mathematical model of fibrous networks, which reproduces qualitative features of collagen gel's stress–strain response and provides insight into the key features which impact the Young's modulus of similar fibrous tissues. This model analyzes the relationship of the Young's modulus...

... in their elasticities. In this study, we determined the Young’s modulus of hESCs by atomic force microscopy using a pyramidal tip. Using this method we are able to take point measurements of elasticity at multiple locations on a single cell, allowing local variations due to cell structure to be identified. We found...

... bioceramics bone calcium compounds calibration cellular biophysics materials preparation mesh generation porosity tissue engineering Young's modulus tissue engineering bone scaffolds cellular solids geometry projection numerical homogenization micro-robotic deposition Natural...

... and the applied preload were different. The Young’s modulus was calculated from a viscoelastic model, and the permeability from a linear biphasic poroviscoelastic model. Important differences were observed in the prediction of the mechanical properties of the IVD according to the initial experimental conditions...

..., 45 min, 125 min, and 245 min) and discal region along the midsagittal profile for each disk grade. A design of experiments was further implemented to analyze the influence of six disk parameters (disk height ( H ) , fiber proportion ( % F ) , drained Young's modulus ( E a , E n ) , and initial...

... the tests on the scaffold mechanical properties as they degrade. To validate the developed model, scaffolds were made from the biocompatible polymer polycaprolactone (PCL) mixed with hydroxylapatite (HA) nanoparticles and their mechanical properties were examined in terms of the Young modulus. Based...

... deformation. Depending on the assumed material properties of the ECM and the choice of cost function in the optimization, estimates of the PCM Young's modulus ranged from ∼ 24 kPa to 59 kPa, consistent with previous measurements of PCM properties on extracted chondrons using micropipette aspiration. Taken...

..., and the effect of the ILT analog on the model compliance and stiffness was investigated. The wall materials had similar properties ( E init 2.22 MPa and 1.57 MPa) to aortic tissue at physiological pressures (1.8 MPa (from literature)). ILT analogs had a similar Young’s modulus (0.24 MPa and 0.33 MPa...

...Huiyang Luo; Chenkai Dai; Rong Z. Gan; Hongbing Lu The mechanical behavior of human tympanic membrane (TM) has been investigated extensively under quasistatic loading conditions in the past. The results, however, are sparse for the mechanical properties (e.g., Young's modulus) of the TM at high...

... interaction force between the monomers was estimated to be 11.9 nN . A mechanical model of the tubulin dimer was then constructed and, using the results from MD simulations, Young’s modulus was estimated to be 0.6 GPa . A fine agreement with Young’s modulus values from literature ( 0.1 – 2.5 GPa ) is found...

... cortical bone was tested longitudinally at strain rates ranging between 0.14 – 29.1 s − 1 in compression and 0.08–17 s − 1 in tension. Young’s modulus generally increased, across this strain rate range, for both tension and compression. Strength and strain (at maximum load) increased slightly...

... be determined for different locations over the entire TM, and the in-plane properties can be determined for different quadrants of the TM. 29 08 2006 14 06 2007 01 02 2008 biomechanics biomedical measurement biomembranes ear indentation viscoelasticity Young's modulus tympanic...

.... Retraction force-displacement data from the indentation of polyvinyl alcohol gels were processed using the customized software. Many of the retraction curves exhibited strong adhesive interactions that were absent in extension. We compared the values of Young’s modulus extracted from the retraction data...

...-dimensional finite element analysis was used to compute the cell mechanical response to applied force in tweezer experiments and to explicit the correcting functions which have to be used in order to infer the intrinsic cell Young’s modulus from the apparent elasticity modulus. Our analysis, performed...

... compression data were obtained from testing polyvinyl alcohol gels of known composition. Local elastic properties of tissue-engineered cartilage were also measured by the AFM. All AFM data sets were processed using customized software based on the algorithm, and the extracted values of Young’s modulus were...

... continuous spatial fields for each region. The Young’s modulus was represented as a continuous function computed by a least mean squares method. p -FEMs were used to bound the simulation numerical error and to quantify the modeling assumptions. We validated the FE results with in-vitro experiments on a fresh...

... height ratio and number of baffles on the pressure drop are reflected in the fact that these effectively change the equivalent diameter and length of the cystic duct. The effect of the Young’s modulus on the pressure drop is important only if it is lower than 400 Pa ; above this value, a rigid-walled...

... mechanical contact computerised tomography Young's modulus bone metastases pelvis finite element percutaneous acetabuloplasty In the United States, roughly two-thirds of people afflicted with cancer have bone metastases ( 1 2 ), and over 25% of all cancer patients will develop metastatic...

... response reaches asymptotic limits governed by either the solid matrix (slow indentation velocity, large permeability) or the fluid transport (high indentation velocity, low permeability). Using these results, biphasic properties (Young’s modulus and hydraulic permeability) were estimated by fitting model...