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Keywords: diffusion
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Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2024, 146(12): 121011.
Paper No: BIO-23-1307
Published Online: October 11, 2024
... and trajectories of contiguous protein bolus volumes revealed that flow pulsation was beneficial at bolus break-up and that additional local wall curvature-based geometry irregularities also were. Using certain measures, local solute peak concentration blend-down appeared to be diffusion-dominated even for high...
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111010.
Paper No: BIO-22-1084
Published Online: July 18, 2022
...Gabi Schwartz; Andy Morejon; Thomas M. Best; Alicia R. Jackson; Francesco Travascio Due to lack of full vascularization, the meniscus relies on diffusion through the extracellular matrix to deliver small (e.g., nutrients) and large (e.g., proteins) to resident cells. Under normal physiological...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2019, 141(1): 014502.
Paper No: BIO-18-1187
Published Online: November 19, 2018
...Chris D. DiDomenico; Lawrence J. Bonassar Molecular transport of osteoarthritis (OA) therapeutics within articular cartilage is influenced by many factors, such as solute charge, that have yet to be fully understood. This study characterizes how solute charge influences local diffusion...
Includes: Supplementary data
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2012, 134(10): 101005.
Published Online: October 1, 2012
... and metabolite levels were measured in the peripheral skeletal muscle, normal myocardium, the infarct border zone, and the infarct interior. The diffusion coefficients of fluorescein or FITC-labeled dextran (0.3–70 kD) were measured in these tissues using fluorescence recovery after photobleaching. The vascular...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2010, 132(12): 121012.
Published Online: November 16, 2010
... and established mathematical transport models. Results demonstrate how the bridged μ Lane system was used to generate spatial concentration gradients that resulted in an experimentally measured Dextran diffusivity of ( 0.82 ± 0.01 ) × 10 − 6 cm 2 / s . System fabrication was performed via three different...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2010, 132(6): 061001.
Published Online: April 16, 2010
... conditions were continuities of mass and mass flux. Two parameters were defined to characterize the mass transports in the fluid and porous regions. The porous Damkohler number is the ratio of consumption to diffusion of the substrates in the porous medium. The fluid Damkohler number is the ratio...
Journal Articles
Publisher: ASME
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074002.
Published Online: July 27, 2009
... the transportation of oxygen in the brain tissue is mainly driven by a diffusion process caused by a concentration gradient of oxygen from blood to cells, the spatial organization of the vascular system, in which the oxygen content is higher than in tissue, is a key factor for maintaining effective transportation...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2008, 130(6): 061002.
Published Online: October 8, 2008
... with the chondrocyte must pass through the pericellular environment. A quantitative understanding of the diffusional properties of the PCM may help in elucidating the regulatory role of the PCM in controlling transport to and from the chondrocyte. The diffusivities of fluorescently labeled 70 kDa and 500 kDa dextrans...
Journal Articles
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2007, 129(5): 666–675.
Published Online: February 14, 2007
... over a simple model with an open annular space. Overall, dispersion is > 10 3 times simple molecular diffusion. The result of enhanced dispersion is rapid spread and dilution of the bolus, effectively stirred by fluid movement around the fine structure. Loth , F. , Yardimci , M...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. April 2007, 129(2): 148–155.
Published Online: September 4, 2006
... presented. This mathematical model takes into account the ionic species diffusion, electric potential coupling, and large mechanical deformation. In addition, a correlation between the diffusive hydrogen ions and fixed-charge groups on the hydrogel polymeric chains is established based on the Langmuir...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2006, 128(5): 674–679.
Published Online: February 12, 2006
... of motors with which the organelles are associated, and the mechanical properties of the cytoplasm. This paper presents a study that characterizes the diffusive motion of mitochondria in chondrocytes seeded in agarose constructs and what this implies about the mechanical properties of the cytoplasm. Method...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2005, 127(5): 758–766.
Published Online: May 26, 2005
... approach was adopted to describe diffusion and uptake in the experimental model. Numerical predictions of lactate, based on simple relations for cell metabolism, were found to agree well for low glucose, but not for high glucose medium. Oxygen did not play a role in either case. Given the close association...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2001, 123(1): 106–113.
Published Online: August 24, 2000
... is substituted into Eq. (5 a ), thus linearizing the equation and allowing an implicit differencing scheme. The spatial increment, Δ x = D Δ t / 2 , is one-half of the characteristic diffusion length, so that the mesh will automatically be fine enough to resolve diffusional processes...