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Keywords: intervertebral disc degeneration
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Journal Articles

Impact of Variations in Water Concentration on the Nanomechanical Behavior of Type I Collagen Microfibrils in Annulus Fibrosus

Shambo Bhattacharya, Devendra K. Dubey
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. April 2022, 144(4): 041004.
Paper No: BIO-21-1122
DOI: https://doi.org/10.1115/1.4052563
Published Online: December 1, 2021
... to 2.3 GPa and peak stress increasing from 77.5 MPa to 80 MPa (Fig. 8 ). A water-mediated contact or water bridge formed between two amino acids is shown in Fig. S6( e ) available in the Supplemental Materials . 04 04 2021 24 09 2021 01 12 2021 intervertebral disc degeneration...
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Topics: Water, Stress, Deformation
Includes: Supplementary data
Journal Articles

Mechanical Consequence of Induced Intervertebral Disc Degeneration in the SPARC-Null Mouse

Mitchel C. Whittal, Sara Molladavoodi, Derek P. Zwambag, Magali Millecamps, Laura S. Stone, Diane E. Gregory
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. February 2021, 143(2): 024501.
Paper No: BIO-20-1065
DOI: https://doi.org/10.1115/1.4047995
Published Online: October 8, 2020
... e-mail:  dgregory@wlu.ca 09 02 2020 08 07 2020 08 10 2020 mice neutral zone stiffness axial loading lumbar spine SPARC secreted protein acidic and rich in cysteine intervertebral disc degeneration Intervertebral disc (IVD) degeneration is a driving force...
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Topics: Intervertebral discs, Lumbar spine, Stiffness, Mechanical testing, Proteins, Mechanical properties