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Keywords: remodeling
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Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2024, 146(7): 071009.
Paper No: BIO-23-1411
Published Online: April 17, 2024
... and cyclic strain on matrix remodeling in young tendons, finding that cyclic strain is optimal for studying remodeling in vitro. We then investigated the remodeling response of young and aged tendon explants after 7 days of varied mechanical stimulus (stress deprivation, 1%, 3%, 5%, or 7% cyclic strain) via...
Includes: Supplementary data
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2015, 137(3): 031008.
Paper No: BIO-14-1124
Published Online: March 1, 2015
... is treated as a fiber-reinforced material with the fibers corresponding to the collagenous component. Blood is modeled as a Newtonian fluid with constant density and viscosity; no slip and no-flux conditions are applied at the arterial wall. Disease progression is simulated by growth and remodeling (G&R...
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2014, 136(9): 091007.
Paper No: BIO-14-1088
Published Online: July 15, 2014
... A computational framework was implemented and validated to better understand the hypertensive artery remodeling in both geometric dimensions and material properties. Integrating the stress-modulated remodeling equations into commercial finite element codes allows a better control and visualization of local...
Journal Articles
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021024.
Paper No: BIO-13-1426
Published Online: February 5, 2014
... of the model that did not allow for the physically realistic simulation of fibril mechanics. The significance of the torsional spring constant value was then explored to determine its impact on remodeling of the simulated fibrous network. Although a stronger torsional spring constant reduced the degree...
Includes: Supplementary data
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2009, 131(11): 114502.
Published Online: October 26, 2009
... cardiovascular system medical disorders stress effects opening angle strain intima adventitia remodeling The stress distribution in the vessel wall has important bearing on vascular function in health and disease. We have recently shown that a larger opening angle ( O A ) can...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2009, 131(11): 111011.
Published Online: October 26, 2009
... report a new observation that the circumferential stress at the adventitia may exceed that at the intima at physiological loading due to the larger OA in the porcine coronary artery. This has important implications for growth and remodeling, where an increase in opening angle may shift excessive stress...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101018.
Published Online: October 14, 2009
...Silvia Wognum; David E. Schmidt; Michael S. Sacks The urinary bladder wall (UBW), which is composed of smooth muscle, collagen, and elastin, undergoes profound remodeling in response to changes in mechanical loading resulting from various pathologies. In our laboratory, we have observed...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101015.
Published Online: October 13, 2009
... such models provide. Such microstructurally motivated models will be useful in characterizing vascular growth and remodeling in terms of the evolution of microstructural metrics that may be quantified experimentally. biomechanics blood vessels regression analysis stress effects vascular mechanics...
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. October 2009, 131(10): 104501.
Published Online: September 10, 2009
...Alexander Rachev; Zachary Dominguez; Raymond Vito Organ culture systems are used to study remodeling of arteries and to fabricate tissue engineered vascular grafts. Investigations to date focused on changes in geometry and mechanical response of arteries or constructs associated with controlled...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2004, 126(6): 787–795.
Published Online: February 4, 2005
... equipment medical computing mechanical testing Ex Vivo Perfusion Organ Culture Remodeling Mechanical Properties Vascular Smooth Muscle Endothelium Cell-mediated growth and remodeling in arteries is controlled, in large part, via mechanosensitive responses by endothelial cells (EC...