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Journal Articles

Microstructural Parameter-Based Modeling for Transport Properties of Collagen Matrices

Seungman Park, Catherine Whittington, Sherry L. Voytik-Harbin, Bumsoo Han
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2015, 137(6): 061003.
Paper No: BIO-14-1479
https://doi.org/10.1115/1.4029920
Published Online: June 1, 2015
View Article titled, Microstructural Parameter-Based Modeling for Transport Properties of Collagen Matrices
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Topics: Permeability, Porosity, Fluids, Computational methods, Modeling, Particulate matter
Proceedings Papers

Freezing-Assisted Intracellular Drug Delivery to Multi-Drug Resistant Cancer Cells

Ka Yaw Teo, Bumsoo Han
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 271-272, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192373
https://doi.org/10.1115/SBC2008-192373
View Paper titled, Freezing-Assisted Intracellular Drug Delivery to Multi-Drug Resistant Cancer Cells
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Topics: Cancer, Drug delivery systems, Drugs, Freezing, Cell membranes, Extruding, Pharmacokinetics, Proteins
Proceedings Papers

Spatiotemporal Temperature Measurement Using Quantum Dot Thermometry During Nanoshell Mediated Thermal Therapy

Bumsoo Han, Willard L. Hanson, Karim Bensalah, Altug Tuncel, Joshua Stern, Jeffrey A. Cadeddu
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 97-98, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192658
https://doi.org/10.1115/SBC2008-192658
View Paper titled, Spatiotemporal Temperature Measurement Using Quantum Dot Thermometry During Nanoshell Mediated Thermal Therapy
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Topics: Patient treatment, Quantum dots, Spatiotemporal phenomena, Temperature measurement, Tumors, Biological tissues, Surgery
Proceedings Papers

Freezing-Induced Cell-Fluid-Matrix Interaction in Engineered Tissue

Junkyu Jung, Ka Yaw Teo, J. Craig Dutton, Bumsoo Han
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 895-896, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192208
https://doi.org/10.1115/SBC2008-192208
View Paper titled, Freezing-Induced Cell-Fluid-Matrix Interaction in Engineered Tissue
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Topics: Biological tissues, Fluids, Freezing, Biophysics, Cryonics, Design, Performance, Thawing
Proceedings Papers

Development of Quantum Dot-Embedded Nanoparticles for Biothermal Imaging

Willard L. Hanson, Nancy L. Michael, Choong-Un Kim, Bumsoo Han
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 75-76, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176185
https://doi.org/10.1115/SBC2007-176185
View Paper titled, Development of Quantum Dot-Embedded Nanoparticles for Biothermal Imaging
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Topics: Imaging, Nanoparticles, Biological tissues, Surgery, Cancer, Temperature, Tumors, Blood vessels, Fluorescence, Freezing
Proceedings Papers

Freezing Induced Microstructural Change of Collagen Matrix

Bumsoo Han, Jeffrey D. Miller, Jun K. Jung
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1051-1052, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175251
https://doi.org/10.1115/SBC2007-175251
View Paper titled, Freezing Induced Microstructural Change of Collagen Matrix
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Topics: Freezing, Biological tissues, Biomaterials, Arrhythmias, Biomedicine, Cancer, Cryonics, Mechanical properties, Preservation, Scanning electron microscopy
Journal Articles

Measurement of Spatiotemporal Intracellular Deformation of Cells Adhered to Collagen Matrix During Freezing of Biomaterials

Soham Ghosh, J. Craig Dutton, Bumsoo Han
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021025.
Paper No: BIO-13-1430
https://doi.org/10.1115/1.4026180
Published Online: February 5, 2014
View Article titled, Measurement of Spatiotemporal Intracellular Deformation of Cells Adhered to Collagen Matrix During Freezing of Biomaterials
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Topics: Biological tissues, Deformation, Freezing, Particulate matter, Spatiotemporal phenomena, Biomaterials
Proceedings Papers

Spatiotemporal Intracellular Deformation of Cells During Freezing-Induced Cell-Fluid-Matrix Interactions

Soham Ghosh, J. Craig Dutton, Bumsoo Han
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT49A006, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14673
https://doi.org/10.1115/SBC2013-14673
View Paper titled, Spatiotemporal Intracellular Deformation of Cells During Freezing-Induced Cell-Fluid-Matrix Interactions
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Topics: Deformation, Fluids, Freezing, Spatiotemporal phenomena, Biological tissues, Biomaterials, Tissue engineering, Adhesion, Biology, Biomedicine
Proceedings Papers

Visualizing Chondrocyte Mechanotransduction in 3D

Qiaoqiao Wan, Eunhye Cho, Seungman Park, Bumsoo Han, Hiroki Yokota, Sungsoo Na
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT35A002, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14484
https://doi.org/10.1115/SBC2013-14484
View Paper titled, Visualizing Chondrocyte Mechanotransduction in 3D
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Topics: Chondrocytes, Cartilage, Maintenance, Stress, Adhesion, Biosensors, Energy transformation, Enzymes, Fluorescence, Linkages
Proceedings Papers

Tumor-on-Chip: Simulation of Complex Transport Around Tumor

Bongseop Kwak, Kinam Park, Bumsoo Han
Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T02A006, February 4–6, 2013
Publisher: American Society of Mechanical Engineers
Paper No: NEMB2013-93314
https://doi.org/10.1115/NEMB2013-93314
View Paper titled, Tumor-on-Chip: Simulation of Complex Transport Around Tumor
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Topics: Simulation, Tumors, Biological tissues, Blood, Bridges (Structures), Drugs, Fluid pressure, Microfluidics, Nanoparticles, Performance
Proceedings Papers

Effects of Freezing on Collagen Nanoscale Structure in Engineered Tissues

Altug Ozcelikkale, Yan Li, Xianfan Xu, Bumsoo Han
Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T03A001, February 4–6, 2013
Publisher: American Society of Mechanical Engineers
Paper No: NEMB2013-93125
https://doi.org/10.1115/NEMB2013-93125
View Paper titled, Effects of Freezing on Collagen Nanoscale Structure in Engineered Tissues
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Topics: Biological tissues, Freezing, Nanoscale phenomena, Biomaterials, Cryonics, Performance, Physiology
Proceedings Papers

Nanoscale Fluid-Structure Interactions in Cytoplasm During Freezing

Altug Ozcelikkale, Bumsoo Han
Proc. ASME. IMECE2012, Volume 2: Biomedical and Biotechnology, 711-716, November 9–15, 2012
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2012-88161
https://doi.org/10.1115/IMECE2012-88161
View Paper titled, Nanoscale Fluid-Structure Interactions in Cytoplasm During Freezing
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Topics: Fluid structure interaction, Freezing, Nanoscale phenomena, Space, Cryobiology
Proceedings Papers

Effects of Collagen Microstructure on the Transport Properties of Vascularized Engineered Tissues

Seungman Park, Catherine Whittington, Mervin C. Yoder, Sherry Voytik-Harbin, Bumsoo Han
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 633-634, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80817
https://doi.org/10.1115/SBC2012-80817
View Paper titled, Effects of Collagen Microstructure on the Transport Properties of Vascularized Engineered Tissues
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Topics: Biological tissues, Diseases, Vessels, Biopolymers, Failure, Physiology
Proceedings Papers

Role of Cells in Freezing-Induced Cell-Fluid Matrix Interactions Within Engineered Tissues

Angela Seawright, Altug Ozcelikkale, J. Craig Dutton, Bumsoo Han
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 409-410, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80531
https://doi.org/10.1115/SBC2012-80531
View Paper titled, Role of Cells in Freezing-Induced Cell-Fluid Matrix Interactions Within Engineered Tissues
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Topics: Biological tissues, Fluids, Freezing, Cryonics, Biomedicine, Preservation, Storage, Thawing, Tissue engineering
Proceedings Papers

Functional Imaging of Matrix Structure of Cryopreserved Engineered Tissues Using Back-Directional Gated Mesoscopic Imaging

Young L. Kim, Zhengbin Xu, Altug Ozcelikkale, Bumsoo Han
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 259-260, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80692
https://doi.org/10.1115/SBC2012-80692
View Paper titled, Functional Imaging of Matrix Structure of Cryopreserved Engineered Tissues Using Back-Directional Gated Mesoscopic Imaging
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Topics: Biological tissues, Imaging, Mesoscopic systems, Cryonics, Fluids, Freezing, Preservation, Tissue engineering
Proceedings Papers

Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry

Willard Hanson, Najma Abdollahzadeh, Yaling Liu, Bumsoo Han
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 351-352, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-205517
https://doi.org/10.1115/SBC2009-205517
View Paper titled, Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry
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Topics: Biological tissues, Cancer, Energy resources, Fluorescence, Heating, Lasers, Microwaves, Patient treatment, Quantum dots, Temperature measurement
Proceedings Papers

Spatiotemporal Deformation of Engineered Tissue During Freezing

Ka Yaw Teo, J. Craig Dutton, Bumsoo Han
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 205-206, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206367
https://doi.org/10.1115/SBC2009-206367
View Paper titled, Spatiotemporal Deformation of Engineered Tissue During Freezing
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Topics: Biological tissues, Deformation, Freezing, Spatiotemporal phenomena, Cryonics, Preservation, Biomaterials, Storage
Proceedings Papers

Modified Challenge-Based Teaching of Biotransport Phenomena

Bumsoo Han
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 753-754, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53300
https://doi.org/10.1115/SBC2011-53300
View Paper titled, Modified Challenge-Based Teaching of Biotransport Phenomena
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Topics: Biotransport, Teaching, Students, Bioengineering, Biology, Biomedical engineering, Chemical engineering, Mechanical engineering
Proceedings Papers

A Biphasic Model Illuminating Freezing-Induced Fluid-Matrix Interactions in a Tissue Equivalent

Jamie Wright, Bumsoo Han, Cheng-Jen Chuong
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 755-756, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53321
https://doi.org/10.1115/SBC2011-53321
View Paper titled, A Biphasic Model Illuminating Freezing-Induced Fluid-Matrix Interactions in a Tissue Equivalent
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Topics: Biological tissues, Fluids, Freezing, Deformation, Preservation, Cryonics, Pressure, Stress, Thawing, Transients (Dynamics)
Proceedings Papers

Effects of Freezing-Induced Cell-Fluid-Matrix Interactions on Cells and Extracellular Matrix of Engineered Tissues

Ka Yaw Teo, J. Craig Dutton, Frederick Grinnell, Bumsoo Han
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 133-134, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53407
https://doi.org/10.1115/SBC2011-53407
View Paper titled, Effects of Freezing-Induced Cell-Fluid-Matrix Interactions on Cells and Extracellular Matrix of Engineered Tissues
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Topics: Biological tissues, Fluids, Freezing, Cryonics, Biomedicine, Performance, Tissue engineering