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Proceedings Papers

A Paradigm for Functional Tissue Engineering

David L. Butler
Proc. ASME. IMECE2000, Advances in Bioengineering, 25-26, November 5–10, 2000
Publisher: American Society of Mechanical Engineers
Paper No: IMECE2000-2497
https://doi.org/10.1115/IMECE2000-2497
View Paper titled, A Paradigm for Functional Tissue Engineering
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Topics: Tissue engineering, Biological tissues, Maintenance, Biomechanics, Engineers, Surgery, Blood vessels, Bone, Cardiovascular system, Cartilage
Proceedings Papers

Col1 and Col2 Gene Expression During the Development of Murine Knee Joints

Kumar Chokalingam, Chris Frede, Jane L. Florer, Richard J. Wenstrup, David L. Butler
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 373-374, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192596
https://doi.org/10.1115/SBC2008-192596
View Paper titled, Col1 and Col2 Gene Expression During the Development of Murine Knee Joints
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Topics: Biological tissues, Biology, Engineers, Knee, Maintenance, Tendons
Proceedings Papers

Comparative Histological and Biomechanical Effects of Prostaglandin-E2 and Bacterial Collagenase on the Rabbit Patellar Tendon

Nathaniel A. Dyment, Jason T. Shearn, Marc T. Galloway, R. Michael Greiwe, Keith Kenter, Samer S. Hasan, David L. Butler, Gregory P. Boivin
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 275-276, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192395
https://doi.org/10.1115/SBC2008-192395
View Paper titled, Comparative Histological and Biomechanical Effects of Prostaglandin-E2 and Bacterial Collagenase on the Rabbit Patellar Tendon
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Topics: Biomechanics, Tendons, Fibroblasts, Rupture
Proceedings Papers

Effect of Anterior Translation on Anterior Knee Force in a Porcine Model

Daniel V. Boguszewski, Jason T. Shearn, Christopher T. Wagner, David L. Butler
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 375-376, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192597
https://doi.org/10.1115/SBC2008-192597
View Paper titled, Effect of Anterior Translation on Anterior Knee Force in a Porcine Model
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Topics: Knee, Anterior cruciate ligament, Wounds, Failure, Robotics, Accounting, Bearings, Biomechanics, Magnetic resonance imaging, Stability
Proceedings Papers

Biomechanical Comparison of Abdominal Wall Hernia Repair Materials

Daniel V. Boguszewski, Nathaniel A. Dyment, Denis L. Bailey, Jason T. Shearn, David L. Butler
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 89-90, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192615
https://doi.org/10.1115/SBC2008-192615
View Paper titled, Biomechanical Comparison of Abdominal Wall Hernia Repair Materials
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Topics: Biomechanics, Maintenance, Synthetic products, Adhesion, Surgery, Testing, Failure, Mechanical properties, Physiology, Soft tissues
Proceedings Papers

Evaluation of a Novel Scaffold Material for Tendon Tissue Engineering

Victor S. Nirmalanandhan, Kirsten R. C. Kinneberg, Natalia Juncosa-Melvin, Heather M. Powell, Marepalli Rao, Steven T. Boyce, David L. Butler
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1005-1006, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176294
https://doi.org/10.1115/SBC2007-176294
View Paper titled, Evaluation of a Novel Scaffold Material for Tendon Tissue Engineering
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Topics: Tendons, Maintenance, Biological tissues, Wounds, Biomechanics, Soft tissues, Stem cells, Stiffness, Tissue engineering
Proceedings Papers

Combined Effect of Glycosaminoglycan and Mechanical Stimulation on the In Vitro Biomechanics of Tissue Engineered Tendon Constructs

Kirsten R. C. Kinneberg, Victor S. Nirmalanandhan, Heather M. Powell, Steven T. Boyce, David L. Butler
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1007-1008, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176386
https://doi.org/10.1115/SBC2007-176386
View Paper titled, Combined Effect of Glycosaminoglycan and Mechanical Stimulation on the In Vitro Biomechanics of Tissue Engineered Tendon Constructs
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Topics: Biological tissues, Biomechanics, Tendons, Maintenance, Stiffness, Wounds, Tissue engineering, Freezing, Musculoskeletal system, Performance
Proceedings Papers

Mechanical Stimulation Increases Collagen Type I and Collagen Type III Gene Expression of Stem Cell: Collagen Sponge Constructs for Patellar Tendon Repair

Natalia Juncosa-Melvin, Karl S. Matlin, Robert W. Holdcraft, Victor S. Nirmalanandhan, David L. Butler
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 981-982, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175807
https://doi.org/10.1115/SBC2007-175807
View Paper titled, Mechanical Stimulation Increases Collagen Type I and Collagen Type III Gene Expression of Stem Cell: Collagen Sponge Constructs for Patellar Tendon Repair
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Topics: Maintenance, Stem cells, Tendons, Biological tissues, Biomaterials, Soft tissues, Stiffness
Proceedings Papers

Effect of Mechanical Stimulation on the Biomechanics of Stem Cell: Collagen Sponge Constructs for Patellar Tendon Repair

Natalia Juncosa-Melvin, Jason T. Shearn, Marc T. Galloway, Gregory P. Boivin, Cynthia Gooch, David L. Butler
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 983-984, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-175814
https://doi.org/10.1115/SBC2007-175814
View Paper titled, Effect of Mechanical Stimulation on the Biomechanics of Stem Cell: Collagen Sponge Constructs for Patellar Tendon Repair
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Topics: Biomechanics, Maintenance, Stem cells, Tendons, Biological tissues, Biomaterials, Soft tissues, Stiffness
Proceedings Papers

Analysis of Regional Strain Patterns Following Surgical Disruption of the Enthesis in a Murine Model of Patellar Tendon Injury

Steven D. Gilday, Chris Casstevens, Jason T. Shearn, David L. Butler
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT37A005, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14569
https://doi.org/10.1115/SBC2013-14569
View Paper titled, Analysis of Regional Strain Patterns Following Surgical Disruption of the Enthesis in a Murine Model of Patellar Tendon Injury
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Topics: Surgery, Tendons, Wounds, Bone, Maintenance, Biomechanics, Failure, Junctions, Mechanical properties, Performance
Proceedings Papers

Combined Effects of Scaffold Material and Mechanical Stimulation on the Formation of Tissue Engineered Constructs Using Tendon and Ligament Progenitor Cells

Andrew P. Breidenbach, Nathaniel A. Dyment, Yinhui Lu, Jason T. Shearn, David W. Rowe, Karl E. Kadler, David L. Butler
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT39A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14379
https://doi.org/10.1115/SBC2013-14379
View Paper titled, Combined Effects of Scaffold Material and Mechanical Stimulation on the Formation of Tissue Engineered Constructs Using Tendon and Ligament Progenitor Cells
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Topics: Biological tissues, Stem cells, Tendons, Wounds, Maintenance, Mechanical properties, Musculoskeletal system, Thermoelectric coolers, Tissue engineering
Proceedings Papers

Regulation of Tendon Tissue Engineered Construct Stiffness by Culture Time, Mesenchymal Stem Cells and Mechanical Stimulation

Abhishek Jain, Kirsten R. C. Kinneberg, Victor S. Nirmalanandhan, Jason T. Shearn, Heather M. Powell, Cynthia Gooch, David L. Butler
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 1203-1204, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206775
https://doi.org/10.1115/SBC2009-206775
View Paper titled, Regulation of Tendon Tissue Engineered Construct Stiffness by Culture Time, Mesenchymal Stem Cells and Mechanical Stimulation
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Topics: Stem cells, Stiffness, Tendons, Maintenance, Surgery, Thermoelectric coolers, Wounds, Biological tissues, Biomechanics, Economics
Proceedings Papers

Functional Tissue Engineering for Repair of Load-Bearing Musculoskeletal Tissues: History and Perspective

David L. Butler
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 669-670, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53533
https://doi.org/10.1115/SBC2011-53533
View Paper titled, Functional Tissue Engineering for Repair of Load-Bearing Musculoskeletal Tissues: History and Perspective
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Topics: Bearings, Biological tissues, Maintenance, Musculoskeletal system, Stress, Tissue engineering, Bioreactors, Design, Engineers, Biomaterials
Proceedings Papers

Characterization of a Biomechanical Animal Model for Intact Knee Kinematics and ACL Function Using 6-DOF Robotic Technology

Daniel V. Boguszewski, Safa T. Herfat, Christopher T. Wagner, David L. Butler, Jason T. Shearn
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 645-646, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53658
https://doi.org/10.1115/SBC2011-53658
View Paper titled, Characterization of a Biomechanical Animal Model for Intact Knee Kinematics and ACL Function Using 6-DOF Robotic Technology
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Topics: Anterior cruciate ligament, Biomechanics, Kinematics, Knee, Robotics, Degrees of freedom, Design, Displacement, Maintenance, Osteoarthritis
Proceedings Papers

MPC-Collagen Gel Biologic Augmentations do not Promote Patellar Tendon Integration Into Bone

Kirsten R. C. Kinneberg, Marc T. Galloway, David L. Butler, Jason T. Shearn
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1021-1022, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53778
https://doi.org/10.1115/SBC2011-53778
View Paper titled, MPC-Collagen Gel Biologic Augmentations do not Promote Patellar Tendon Integration Into Bone
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Topics: Bone, Tendons, Maintenance, Design, Failure, Surgery
Proceedings Papers

The Relationships Among Spatiotemporal Gene Expression, Histology, and Biomechanics Following Full-Length Injury in the Murine Patellar Tendon

Nathaniel A. Dyment, Namdar Kazemi, Lindsey E. Aschbacher-Smith, Nicolas J. Barthelery, Keith Kenter, Cynthia Gooch, Jason T. Shearn, Christopher Wylie, David L. Butler
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 493-494, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53622
https://doi.org/10.1115/SBC2011-53622
View Paper titled, The Relationships Among Spatiotemporal Gene Expression, Histology, and Biomechanics Following Full-Length Injury in the Murine Patellar Tendon
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Topics: Biomechanics, Spatiotemporal phenomena, Tendons, Wounds, Biological tissues, Bone, Musculoskeletal system, Proteins, Surgery
Proceedings Papers

Effect of ACL Reconstruction Graft Material on Joint Force Loss During Cyclic Fatigue Testing Using a 6-DOF Motion

Daniel V. Boguszewski, Jason T. Shearn, Christopher T. Wagner, David L. Butler
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 855-856, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19294
https://doi.org/10.1115/SBC2010-19294
View Paper titled, Effect of ACL Reconstruction Graft Material on Joint Force Loss During Cyclic Fatigue Testing Using a 6-DOF Motion
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Topics: Anterior cruciate ligament, Fatigue testing, Kinematics, Knee, Wounds, Cartilage, Cycles, Osteoarthritis, Performance, Stability
Proceedings Papers

Effects of Tensile Stimulation on Gene Expression and In Vitro Stiffness of Murine Tissue Engineered Constructs

Nathaniel A. Dyment, Kumar Chokalingam, Amanda Shoemaker, Cynthia Gooch, Christopher Wylie, Jason T. Shearn, David L. Butler
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 963-964, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19120
https://doi.org/10.1115/SBC2010-19120
View Paper titled, Effects of Tensile Stimulation on Gene Expression and In Vitro Stiffness of Murine Tissue Engineered Constructs
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Topics: Biological tissues, Stiffness, Thermoelectric coolers, Wounds, Maintenance, Performance, Tendons, Engineering simulation, Engineers, Musculoskeletal system
Journal Articles

Evolving Strategies in Mechanobiology to More Effectively Treat Damaged Musculoskeletal Tissues

David L. Butler, Nathaniel A. Dyment, Jason T. Shearn, Kirsten R. C. Kinneberg, Andrew P. Breidenbach, Andrea L. Lalley, Steven D. Gilday, Cynthia Gooch, M. B. Rao, Chia-feng Liu, Christopher Wylie
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021001.
Paper No: BIO-12-1475
https://doi.org/10.1115/1.4023479
Published Online: February 7, 2013
View Article titled, Evolving Strategies in Mechanobiology to More Effectively Treat Damaged Musculoskeletal Tissues
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Topics: Biological tissues, Musculoskeletal system, Tendons, Biomechanics, Mechanobiology, Wounds, Tissue engineering
Journal Articles

Effect of Implanting a Soft Tissue Autograft in a Central-Third Patellar Tendon Defect: Biomechanical and Histological Comparisons

Kirsten R. C. Kinneberg, Marc T. Galloway, David L. Butler, Jason T. Shearn
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. September 2011, 133(9): 091002.
https://doi.org/10.1115/1.4004948
Published Online: October 4, 2011
View Article titled, Effect of Implanting a Soft Tissue Autograft in a Central-Third Patellar Tendon Defect: Biomechanical and Histological Comparisons
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Topics: Biological tissues, Biomechanics, Bone, Maintenance, Surgery, Tendons, Soft tissues