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Proceedings Papers

Direct Hydraulic Permeability Measurements of Agarose Hydrogels Used as Cell Scaffolds

Michael A. Soltz, Anna Stankiewicz, Gerard Ateshian, Robert L. Mauck, Clark T. Hung

Proc. ASME. IMECE99, Advances in Bioengineering, 229-230, November 14–19, 1999

Paper No: IMECE1999-0461

DOI: https://doi.org/10.1115/IMECE1999-0461

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Topics: Agar, Hydrogels, Permeability, Fluids, Chondrocytes, Cartilage, Fluid dynamics, Bearings, Compacting, Ions

Proceedings Papers

Is Articular Cartilage Orthotropic in Compression?

Michael A. Soltz, Robert L. Mauck, Clark T. Hung, Gerard A. Ateshian

Proc. ASME. IMECE99, Advances in Bioengineering, 209-210, November 14–19, 1999

Paper No: IMECE1999-0451

DOI: https://doi.org/10.1115/IMECE1999-0451

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Topics: Cartilage, Compression, Tension, Anisotropy, Biological tissues, Strips

Proceedings Papers

Chondrocyte Translocation and Orientation to Applied DC Electric Fields

Robert L. Mauck, Pen-hsiu G. Chao, Beth Gilbert, Wilmot B. Valhmu, Clark T. Hung

Proc. ASME. IMECE99, Advances in Bioengineering, 117-118, November 14–19, 1999

Paper No: IMECE1999-0405

DOI: https://doi.org/10.1115/IMECE1999-0405

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Topics: Chondrocytes, Electric fields, Cartilage, Bioengineering, Biological tissues, Bone, Cornea, Fibroblasts, Maintenance, Shapes

Proceedings Papers

Time-Varying Effect of Ascorbate on the Compressive Modulus and Gag Content of Chondrocyte-Seeded Agarose Cultures

Robert L. Mauck, Michael A. Soltz, Beth Gilbert, Gerard A. Ateshian, Clark T. Hung, Frank J. Raia, Wilmot B. Valhmu

Proc. ASME. IMECE99, Advances in Bioengineering, 105-106, November 14–19, 1999

Paper No: IMECE1999-0399

DOI: https://doi.org/10.1115/IMECE1999-0399

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Topics: Agar, Chondrocytes, Disks, Cartilage, Mechanical properties, Assaying, Biological tissues

Proceedings Papers

Mechanical Loading Modulates Gene Expression in Chondrocyte-Seeded Agarose Hydrogels

Sansan S. Lo, Robert L. Mauck, Sara L. Seyhan, Glyn D. Palmer, Van C. Mow, Clark T. Hung

Proc. ASME. IMECE2001, Advances in Bioengineering, 291-292, November 11–16, 2001

Paper No: IMECE2001/BED-23145

DOI: https://doi.org/10.1115/IMECE2001/BED-23145

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Topics: Agar, Chondrocytes, Hydrogels, Cartilage, Stress, Biological tissues, Bearings, Bioreactors, Compression, Dynamic testing (Materials)

Proceedings Papers

Dynamic Hydrostatic Pressurization Increases Matrix Gene Expression by Chondrocytes in 3D Culture

Robert L. Mauck, Michael A. Soltz, Gerard A. Ateshian, Clark T. Hung

Proc. ASME. IMECE2001, Advances in Bioengineering, 295-296, November 11–16, 2001

Paper No: IMECE2001/BED-23147

DOI: https://doi.org/10.1115/IMECE2001/BED-23147

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Topics: Chondrocytes, Hydrostatics, Cartilage, Hydrostatic pressure, Pressure, Stress, Bearings, Bone, Deformation, Hydrogels

Proceedings Papers

A Novel Device for Direct Permeation Measurements of Hydrogels and Soft Hydrated Tissues

Nelly A. Andarawis, Sara L. Seyhan, Robert L. Mauck, Michael A. Soltz, Gerard A. Ateshian, Clark T. Hung

Proc. ASME. IMECE2001, Advances in Bioengineering, 299-300, November 11–16, 2001

Paper No: IMECE2001/BED-23149

DOI: https://doi.org/10.1115/IMECE2001/BED-23149

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Topics: Biological tissues, Hydrogels, Permeability, Cartilage, Deformation, Fluids, Agar, Bearings, Design, Lubrication

Proceedings Papers

Dynamic Compression Stimulates the Development of Equilibrium Aggregate Modulus in Tissue Engineered Cartilage Constructs

Robert L. Mauck, Glyn D. Palmer, Christopher C.-B. Wang, Michael A. Soltz, Wilmot B. Valhmu, Gerard A. Ateshian, Clark T. Hung

Proc. ASME. IMECE2000, Advances in Bioengineering, 67-68, November 5–10, 2000

Paper No: IMECE2000-2518

DOI: https://doi.org/10.1115/IMECE2000-2518

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Topics: Biological tissues, Cartilage, Compression, Equilibrium (Physics), Agar, Bearings, Functional materials, Physiology, Stress, Tissue engineering

Proceedings Papers

Cathodal Migration of Chondrocytes to Applied DC Electric Fields: Effects of Neomycin

Pen-hsiu G. Chao, Wendy Liu, Rani Roy, Robert L. Mauck, Clark T. Hung

Proc. ASME. IMECE2000, Advances in Bioengineering, 65-66, November 5–10, 2000

Paper No: IMECE2000-2517

DOI: https://doi.org/10.1115/IMECE2000-2517

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Topics: Chondrocytes, Electric fields, Temperature, Cartilage, Maintenance, Physiology

Journal Articles

The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction

Spencer E. Szczesny, Robert L. Mauck

J Biomech Eng. February 2017, 139(2): 021006.

Paper No: BIO-16-1276

DOI: https://doi.org/10.1115/1.4035350

Published Online: January 19, 2017

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Topics: Fibers, Membranes, Proteins, Stiffness, Stress, Tension, Deformation, Cell membranes, Cellular mechanics, Stem cells

Proceedings Papers

Mechanics and Cytocompatibility of Genipin Crosslinked Type I Collagen Nanofibrous Scaffolds

Albert O. Gee, Brendon M. Baker, Robert L. Mauck

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 703-704, June 25–29, 2008

Paper No: SBC2008-193220

DOI: https://doi.org/10.1115/SBC2008-193220

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Topics: Anisotropy, Biological tissues, Biomimetics, Electrospinning, Ethyl compounds, Fibers, Maintenance, Mechanical properties, Musculoskeletal system, Orthopedics

Proceedings Papers

Hyaluronic Acid Macromer Concentration Influences Functional MSC Chondrogenesis in Photocrosslinked MSC-Laden Hydrogels

Isaac E. Erikson, Cindy Chung, Jason A. Burdick, Robert L. Mauck

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 643-644, June 25–29, 2008

Paper No: SBC2008-193096

DOI: https://doi.org/10.1115/SBC2008-193096

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Topics: Hydrogels, Cartilage, Chondrocytes, Maintenance, Molecular weight, Optimization, Tissue engineering

Proceedings Papers

High-Throughput Screening of Chemical Libraries for Modulators of Mesenchymal Stem Cell Chondrogenesis

Alice H. Huang, Nuzhat A. Motlekar, Ashley Stein, Eileen M. Shore, Scott L. Diamond, Robert L. Mauck

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 1055-1056, June 25–29, 2008

Paper No: SBC2008-193118

DOI: https://doi.org/10.1115/SBC2008-193118

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Topics: Stem cells, Assaying, Cartilage, Robotics, Biological tissues, Bone, Density, Tissue engineering

Proceedings Papers

Transient Exposure to TGF-B3 Improves Mechanical Properties of MSC-Laden Constructs

Alice H. Huang, Ashley Stein, Meira Yeger-McKeever, Rocky S. Tuan, Robert L. Mauck

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 57-58, June 25–29, 2008

Paper No: SBC2008-193130

DOI: https://doi.org/10.1115/SBC2008-193130

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Topics: Mechanical properties, Transients (Dynamics), Chondrocytes, Cartilage, Density, Hydrogels, Biological tissues, Enzymes, Parity (Physics), Shock (Mechanics)

Proceedings Papers

Fabrication and Modeling of an Electrospun Tri-Polymer Composite for the Engineering of Fibrous Tissues

Brendon M. Baker, Nandan L. Nerurkar, Jason A. Burdick, Dawn M. Elliott, Robert L. Mauck

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 973-974, June 25–29, 2008

Paper No: SBC2008-193174

DOI: https://doi.org/10.1115/SBC2008-193174

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Topics: Biological tissues, Composite materials, Manufacturing, Modeling, Polymers, Fibers, Anisotropy, Electrospinning, Muscle, Packing (Shipments)

Proceedings Papers

Engineered MSC-Laden Cartilage Constructs are Sensitive to Inflammatory Cytokine-Mediated Degradation

Meira Yeger-McKeever, Alice H. Huang, Ashley F. Stein, Robert L. Mauck

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 993-994, June 20–24, 2007

Paper No: SBC2007-176186

DOI: https://doi.org/10.1115/SBC2007-176186

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Topics: Cartilage, Chondrocytes, Maintenance, Surgery, Artificial limbs, Biological tissues, Bone, Diseases, Stem cells, Tissue engineering

Proceedings Papers

Electrospinning of Photopolymerizable Poly(β-Amino Ester) Networks for Fibrous Tissue Engineering

Andrea R. Tan, Jamie L. Ifkovits, Brendon M. Baker, Robert L. Mauck, Jason A. Burdick

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 997-998, June 20–24, 2007

Paper No: SBC2007-176206

DOI: https://doi.org/10.1115/SBC2007-176206

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Topics: Biological tissues, Damage, Electrospinning, Ester, Fibers, Intervertebral discs, Knee, Musculoskeletal system, Tendons, Tissue engineering

Proceedings Papers

Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels

Alice H. Huang, Robert L. Mauck

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1011-1012, June 20–24, 2007

Paper No: SBC2007-176427

DOI: https://doi.org/10.1115/SBC2007-176427

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Topics: Agar, Anisotropy, Bearings, Biological tissues, Bioreactors, Cartilage, Chondrocytes, Diseases, Friction, Hydrogels

Proceedings Papers

Multi-Lamellar and Multi-Axial Maturation of Cell-Seeded Fiber-Reinforced Tissue Engineered Constructs

Brendon M. Baker, Grace D. O’Connell, Sounok Sen, Ashwin S. Nathan, Dawn M. Elliott, Robert L. Mauck

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1013-1014, June 20–24, 2007

Paper No: SBC2007-176434

DOI: https://doi.org/10.1115/SBC2007-176434

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Topics: Biological tissues, Fibers, Knee, Annulus, Anisotropy, Bearings, Intervertebral discs, Laminates, Mechanical properties, Nanoscale phenomena

Proceedings Papers

Enhanced Cellular Infiltration With Removal of Sacrificial Fibers From a Dual-Polymer Nanofibrous Scaffold

Robert B. Metter, Jr., Brendon M. Baker, Jason A. Burdick, Robert L. Mauck

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1017-1018, June 20–24, 2007

Paper No: SBC2007-176487

DOI: https://doi.org/10.1115/SBC2007-176487

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Topics: Fibers, Polymers, Stress, Biological tissues, Knee, Osteoarthritis, Tension, Wedges, Wounds

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Journal citation

NARROW

Direct Hydraulic Permeability Measurements of Agarose Hydrogels Used as Cell Scaffolds

Is Articular Cartilage Orthotropic in Compression?

Chondrocyte Translocation and Orientation to Applied DC Electric Fields

Time-Varying Effect of Ascorbate on the Compressive Modulus and Gag Content of Chondrocyte-Seeded Agarose Cultures

Mechanical Loading Modulates Gene Expression in Chondrocyte-Seeded Agarose Hydrogels

Dynamic Hydrostatic Pressurization Increases Matrix Gene Expression by Chondrocytes in 3D Culture

A Novel Device for Direct Permeation Measurements of Hydrogels and Soft Hydrated Tissues

Dynamic Compression Stimulates the Development of Equilibrium Aggregate Modulus in Tissue Engineered Cartilage Constructs

Cathodal Migration of Chondrocytes to Applied DC Electric Fields: Effects of Neomycin

The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction

Mechanics and Cytocompatibility of Genipin Crosslinked Type I Collagen Nanofibrous Scaffolds

Hyaluronic Acid Macromer Concentration Influences Functional MSC Chondrogenesis in Photocrosslinked MSC-Laden Hydrogels

High-Throughput Screening of Chemical Libraries for Modulators of Mesenchymal Stem Cell Chondrogenesis

Transient Exposure to TGF-B3 Improves Mechanical Properties of MSC-Laden Constructs

Fabrication and Modeling of an Electrospun Tri-Polymer Composite for the Engineering of Fibrous Tissues

Engineered MSC-Laden Cartilage Constructs are Sensitive to Inflammatory Cytokine-Mediated Degradation

Electrospinning of Photopolymerizable Poly(β-Amino Ester) Networks for Fibrous Tissue Engineering

Sliding Contact Modulates ECM Expression in Chondroctye-Laden Agarose Gels

Multi-Lamellar and Multi-Axial Maturation of Cell-Seeded Fiber-Reinforced Tissue Engineered Constructs

Enhanced Cellular Infiltration With Removal of Sacrificial Fibers From a Dual-Polymer Nanofibrous Scaffold

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