This paper presents the results from an international survey that investigated the impacts of the built environment on occupant well-being during the corona virus disease 2019 (COVID-19) pandemic when most professionals were forced to work from home (WFH). The survey was comprised of 81 questions focusing on the respondent's profiles, residences, home indoor environmental quality, health, and home working experiences. A total of 1460 responses were collected from 35 countries, and 1137 of them were considered complete for the analysis. The results suggest that home spatial layout has a significant impact on occupant well-being during WFH since home-life distractions and noises due to the lack of a personal workspace are likely to prevent productive work. Lack of scenic views, inadequate daylighting, and poor acoustics were also reported to be detrimental to occupant productivity and the general WFH experience. It is also revealed from this survey that temperature, relative humidity, and indoor air quality generally have higher satisfaction ratios compared with the indoor lighting and acoustic conditions, and the home layout. Hence, home design for lighting, acoustics, and layout should also receive greater attention in the future.